IBioBA (CONICET – Max Planck Partner) researcher Lucas Pontel and his team have just published a paper in Nature Communications describing a new mechanism of damage caused by a group of carcinogenic compounds known as aldehydes. They identified that formaldehyde attacks the antioxidant defenses of cells, and described the factors that prevent this damage. This…
Speaker: Adrian E. Granada – Humboldt-Universität zu Berlin. Title: Single cell cell-fate choices in response to Cisplatin. Abstract: Cells within a single tumor display great diversity at their epigenetic, transcriptome and proteome states. These internal factors alone can generate significant phenotypic and behavioral heterogeneity and thereupon variation in response to drugs. Chemotheraputic DNA damaging agents…
Mariana Fuertes- Photo: IBioBA, CONICET-MPSP. Researcher at IBioBA describe for the first time a mechanism used by these cells to divide, uncontrolled. The group led by Eduardo Arzt, director of the IBioBA and senior researcher of CONICET, published a new study in the journal Endocrine-Related Cancer, where they demonstrate for the first time how the…