Lucas Pontel studied Biotechnology at the National University of Rosario, Argentina. He obtained his Ph.D. in Biological Sciences and later received his first postdoc at the Institute of Molecular and Cellular Biology of Rosario (2010-2012). As part of this postdoc, he spent some months working at the University of California at Irvine (USA).
In 2012 he joined the Laboratory of Molecular Biology, Medical Research Council, in Cambridge, UK. He was appointed as Max Planck-CONICET Research Group Leader to lead the group Cancer Metabolism at IBioBA-MPSP, which he leads since April 2017.
Selected publications
- Reingruber, H., Pontel, L.B.
Formaldehyde Metabolism and Its Impact on Human Health.
C Op Tox 9:28-34 (2018) - Pontel, L.B.*, Langenick, J., Rosado, I.V., Zhang, X-Y., Traynor, D., Kay,R.R., Patel,K.J.*
Xpf suppresses mutagenic consequences of bacterial phagocytosis in Dictyostelium.
Cell Sci Nov:4-10 (2016) *Co-leading authors. - Burgos-Barragan, G., Wit, N., Meiser, J., Dingler, F., Pietzke, M., Mulderrig, L., Pontel, L.B., Rosado, I.V., Brewer, T.F., Cordell, R.L, Monks, P.S., Chang, C.J., Vazquez, A., Patel, K.J.
Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism.
Nature, 2017 Aug 31;548(7669):549-554. - Pontel, L.B., Rosado, I.V., Burgos, G., Garaycoechea, J., Yu, R., Arends, M., Chandrasekaran, G., Broecker, V., Wei, W., Liu, L., Swenberg, J., Crossan, G., Patel K.J.
Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen.
Mol Cell 60:177-88 (2015)