A recent publication of the group of Susana Silbertein in J Cell Biology shows that in the neuronal signals the message is important but also were and when it is started.
The work has been commented in a “Spotlight” article Spatial resolution of cAMP signaling by soluble adenylyl cyclase, by G Caldieri and S Sigismund, J. Cell Biol. 214:125-7, 2016.
This publication is a new important collaboration of our Institute with the Max Planck Institute of Psychiatry in Munich.
Inda C, dos Santos Claro PA, Bonfiglio JJ, Senin S, Maccarrone G, Turck CW, Silberstein S.
Different cAMP sources are critically involved in G protein-coupled receptor CRHR1 signaling.
J. Cell Biol. 214:181-95, 2016.