The research of the Max-Planck Heart and Lung Research Group (MP-HL lab) focuses on the mechanistic bases of hypoxia, senescence, inflammation and repair of the cardio-pulmonary system.

The MPI of Heart and Lung Research is joining forces and sharing tools with IBioBA’s research expertise in the field of cerebral abnormalities and neuro-vascular diseases.

Research topics include, among others:

  • The role of the RSUME-VHL-HIF axis in hypoxia and ischemia driven diseases of the cardio-pulmonary system.
  • Role of the RSUME-NFκB axis in inflammatory lung diseases.
  • Cytokines in senescence.
  • Computional chemistry and drug design in the context of G-protein coupled receptor ligands.
  • The role of macrophages and their functional phenotypes in acute lung injury and repair mechanisms.

Contact MPI-HL research group

Group Head

Prof. Werner Seeger


Dr. med. vet. Mareike Gierhardt (Hypoxia)

Dr. Balachandar Selvakumar (Injury and repair)

This laboratory is operational at and is affiliated to IBioBA